Protocol - History of Being Breast-Fed - Adult

Personnel and Training Required

The interviewer must be trained to conduct personal interviews with individuals from the general population. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews.*

* There are multiple modes to administer this question (e.g., paper-and-pencil and computer-assisted interviews).

Equipment Needs

While the source instrument was administered in-person via a paper-and-pencil instrument, the PhenX Working Group acknowledges that these questions can be administered in a computerized format (i.e., computer-assisted personal interview). Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer or handheld computer to administer a computer-assisted questionnaire.

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Interviewer-administered questionnaire

Lifestage

Adolescent, Adult

Participants

Any age

Selection Rationale

This is a simple question that captures the basic information needed about whether or not the person was breast-fed.

Language

Chinese, English, Other languages available at source

Standards

Standard	Name	ID	Source
Logical Observation Identifiers Names and Codes (LOINC)	Environ exp hx breast fed proto	62532-7	LOINC
Human Phenotype Ontology	Triggered by breast feeding	HP:0025206	HPO
Human Phenotype Ontology	Feeding difficulties in infancy	HP:0008872	HPO
caDSR Form	PhenX PX061001 - History Of Being Breast Fed	5869503	caDSR Form

Derived Variables

None

Process and Review

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on May 31, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 01, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 02, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 03, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 04, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 05, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 06, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 07, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 08, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 09, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 10, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 11, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 12, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

The Expert Review Panel 2 - Demographics, Environmental Exposures, and Social Environment domains reviewed this protocol on Jun 13, 2016. Changes include:

• Minor edits
  • This affects the following fields: Code; Name; Protocol Name from Source; Description; Protocol; Reference; Source; Equipment Needs; Specific Instructions; Selection Rationale; Status; Process and Review; Lifestage; Language;

Protocol Name from Source

National Institutes of Health (NIH), Long Island Breast Cancer Study, 1996

Source

National Institutes of Health, National Cancer Institute. (1996). Long Island Breast Cancer Study. Section M: Pregnancy Related Problems. Question number M1a (Question 1).

General References

Centers for Disease Control and Prevention. (2015). Breastfeeding. Atlanta, GA: Author. http://www.cdc.gov/breastfeeding/

Miotti, P. G., Taha, T. E., Kumwenda, N. I., Broadhead, R., Mtimavalye, L.A., Van der Hoeven, L., . . . Biggar, R. J. (1999). HIV transmission through breastfeeding: A study in Malawi. JAMA, 282(8), 744-749.

Needham, L. L., & R. Y. Wang. (2002). Analytic considerations for measuring environmental chemicals in breast milk. Environmental Health Perspectives, 110(6), A317-A324.

Protocol ID

61001

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX061001_Being_Breast_Fed
	PX061001010000	Did your mother breastfeed you?	Variable Mapping

Environmental Exposures

Measure Name

History of Being Breast Fed

Release Date

October 30, 2009

Definition

Question about whether or not the respondent was breast-fed as a child.

Purpose

Human milk has health benefits for infants (i.e., nutritional and immunologic benefits). Lactation has been shown to be beneficial to the health of mothers (e.g., lower risk of some cancers). Breast-feeding also has been shown to have psychological and neurodevelopmental benefits. Unfortunately, human milk may also be a vehicle for transfer of viruses (e.g., HIV) and environmental chemicals (e.g., polyhalogenated chemicals). Generally, the benefits of human milk and lactation have been found to outweigh the risks of exposures to pathogens or toxic substances in breast milk but there are higher-risk situations that have been recognized. Researchers can use information about breast-feeding to make inferences relevant to early nutritional status and immunologic development, the mother-child relationship, and potential exposures.

Keywords

Environmental Exposures, breast-feeding, breast milk, lactation, immunology, virus transmission, National Cancer Institute, NCI, Long Island Breast Cancer Study, LIBCSP

Measure Protocols

Protocol ID	Protocol Name
61001	History of Being Breast-Fed - Adult
61002	History of Being Breast-Fed - Child